Product Description
Product Description
Products Description
Efavirenz powder is a specific drug against HIV. It is a drug belonging to the class of non-nucleoside reverse transcriptase inhibitors (NNRTI) and can be used in highly active antiretroviral therapy to treat human immunodeficiency virus type 1 (HIV type 1).
How Efavirenz Powder Works
Efavirenz works by inhibiting the reverse transcriptase activity of the virus. Reverse transcriptase is a key enzyme in the HIV replication process that enables the virus to transcribe its RNA genome into DNA and inject it into the host cell. This transcription process is one of the key steps in HIV replication, spread and infection.
Efavirenz binds to reverse transcriptase and blocks the DNA synthesis process of HIV, thereby effectively reducing the replication of the virus. This helps control HIV infection and slows the progression of AIDS. It should be noted that Efavirenz cannot cure HIV or completely eliminate the HIV virus, but it can help maintain the stability of the patient's condition.
COA Of Efavirenz
| Items | Standards | Results |
|---|---|---|
| Appearance | White or off-white powder | Off-white powder |
| Identification | By HPLC | Complies |
| Loss on Drying | ≤1.00% | 0.21% |
| Heavy Metals | ≤10ppm | Complies |
| Sulfated Ash | ≤0.10% | 0.03% |
| Chlorine Content | 17.5%~19.5% | 19.3% |
| Arsenic Content | ≤0.1ppm | 0.09ppm |
| Lead VContent | ≤3.0ppm | 0.50ppm |
| Cadmium Content | ≤0.1ppm | 0.10ppm |
| Mercury Content | ≤0.1ppm | 0.10ppm |
| Microbiological Test | Coliforms:Negative | Negative |
| Salmonella: Negative | Complies | |
| Total plate count: ≤1000 CFU/g | Pass | |
| Yeast&Mold: ≤50 CFU/g | Pass | |
| Related Substances | Impurity A: ≤0.30% | 0.18% |
| Other unknown impurity:≤0.10% | 0.07% | |
| Total Impurities:≤0.50% | 0.42% | |
| Assay | ≥98.0% | 99.50% |
| Conclusion: | Conform with enterprise specification. | |
Changes of Efavirenz in Human Body
Efavirenz will undergo metabolic changes in the liver, and it has both inhibitory and inducing effects on the 3A4 isoform in the cytochrome P450 system. This also means that Efavirenz will have a mutual increase and decrease effect with other drugs in metabolism after reaching the liver, so the dose should be increased or decreased when Efavirenz is used in combination with other drugs. Efavirenz will reduce the blood sugar level of most protease inhibitors. Therefore, it may be necessary to add doses of amprenavir, atazanavir, and indinavir when using it. The level of saquinavir in the blood will also drop sharply after using it, so the two drugs should not be used at the same time. St John's wort and garlic supplements may also reduce the level of efavirenz in the blood.
Side effects of efavirenz
- Common psychopathological symptoms include insomnia, confusion, delirium, memory loss, and depression.
- Rash, nausea, dizziness, and headaches may also occur.
- Efavirenz may cause birth defects and should not be used in women who are pregnant.
- Its safety for infants has not been proven.
- The use of efavirenz may also result in false positive urine tests for marijuana substances.
Packaging and Transportation
General packaging：
- 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
- 5kg/carton(5kg net weight, 5.3kg gross weight, packed in five aluminum foil bag)
- 25kg/drum (25kg net weight, 28kg gross weight;)
Quality Standards and Certifications
Our product adheres to the highest quality standards and holds numerous certifications, ensuring global recognition and trust:
FDA-Salis HALAL ISO CCRE5 USDA Organic EU Organic
Products Description
If you want to buy efavirenz powder please contact us for more details iceyqiang@aliyun.com
Why Choose Us
Salispharm stands apart as a confided in provider of drug unrefined components for a few convincing reasons:
Experienced Research and development Group: Our organization flaunts a full grown innovative work group devoted to guaranteeing the best expectations of item quality and development.
GMP Processing plant: We work a cutting edge fabricating office that sticks to Great Assembling Practices (GMP), ensuring the consistency and virtue of our items.
Enormous Stock: With a significant stock of unrefined components, we can speedily satisfy requests of any size, furnishing our clients with adaptability and inner harmony.
Complete Testaments: Our items are joined by all fundamental endorsements, including FDA-Salis,HALAL, ISO, CCRE5, natural USDA,natural, and EU Natural accreditations, exhibiting our obligation to administrative consistence and quality confirmation.
OEM Administration: We offer far reaching OEM administrations, permitting clients to alter measurement structures and bundling as per their exceptional necessities. Furthermore, we can work with the offer of completed items for those looking for a turnkey arrangement.
Quick Conveyance: We grasp the significance of convenient conveyance and endeavor to speed up the transportation cycle, guaranteeing that our clients accept their orders instantly and proficiently.
Secure Bundling: All items are fastidiously stuffed to forestall tainting and guarantee item trustworthiness during transportation.
FAQ
Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the
samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What's your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery lead time?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
