Product Description
Product Description
What is Lopinavir Powder
Lopinavir Powder is the phosphate salt of chloroquine, a compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.
Function of Lopinavir Powder
Lopinavir Powder has the effects and functions of antiviral, immunomodulatory, liver protection, improvement of lung symptoms, and inhibition of HIV replication.
1. Antiviral
Lopinavir Powder inhibits or kills the virus by blocking the key enzyme protein in the viral replication process.
2. Immunomodulatory
Lopinavir Powder can regulate the body's immune response and enhance the body's defense against pathogens.
3. Liver protection
During the use of Lopinavir Powder, attention should be paid to monitoring liver function to avoid long-term high-dose use causing liver damage.
4. Improve lung symptoms
For patients with respiratory diseases, they should pay close attention to changes in respiratory symptoms during the period of taking the drug and seek medical treatment in time.
5. Inhibition of HIV replication
For patients infected with HIV, regular viral load testing is required to evaluate the treatment effect.
COA of Lopinavir Powder
| ltem | Specification (USP42 Standard) | Result |
|---|---|---|
| Appearance | White powder | White powder |
| Identification | HPLC: The retention time of the test sample corresponds to that of the reference standard | Conform |
| IR: The infrared absorption spectrum of the test sample is concordant with the spectrum of reference standard | Conform | |
| Water content by KF | ≤4.4% | 3.8% |
| Residue on Ignition | ≤0.2% | 0.03% |
| Heavy metals | ≤20ppm | Conform |
| Residue Solvents | Ethanol:≤5000ppm | 200ppm |
| Ethyl acetate:≤5000ppm | ND | |
| Dimethylformamide:≤880ppm | ND | |
| 2-propanol:≤5000ppm | ND | |
| N-heptane:≤5000ppm | 320ppm | |
| Triethylamine:≤720ppm | ND | |
|
Related substances (by HPLC) |
Impurity b (RRT=0.07):≤0.20% | ND |
| Impurityi (RRT=1.10):≤0.20% | ND | |
| Any other impurity:≤0.1% | 0.06% | |
| Any other impurities:≤0.1% | 0.07% | |
| Total impurities from Procedure 1 and Procedure 2:≤0.7% | ||
| Assay (On the anhydrous basis) | Between 98.0% and 102.0% | 99.7% |
| Conclusion | Qualified to USP42. |
Application of Lopinavir Powder
Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite.
Packaging and Transportation:
At Salispharm, we focus on the no problem at all bundling of our items to guarantee their respectability during transportation. It is carefully loaded as per industry guidelines to forestall defilement and keep up with item steadiness. We offer an assortment of bundling choices to oblige different client needs and inclinations. Our effective strategies network empowers quick and dependable transportation of orders to objections around the world, guaranteeing ideal conveyance and consumer loyalty.
Quality Standards and Certifications
Our product adheres to the highest quality standards and holds numerous certifications, ensuring global recognition and trust:
FDA-Salis HALAL ISO CCRE5 USDA Organic EU Organic
Contact US
If you want to buy Lopinavir Powder please contact us for more details iceyqiang@aliyun.com
