Cetirizine hydrochloride Powder is an antihistamine that treats symptoms, such as itching, runny nose, watery eyes, and sneezing from hay fever (allergic rhinitis) and other allergies, such as allergies to molds and dust mites.
1. Antihistamine
Cetirizine hydrochloride blocks histamine receptors and reduces the release of histamine from mast cells, thereby alleviating symptoms caused by allergic reactions.
2. Anticholinergic
The drug has a mild anticholinergic effect and can improve the poor discharge of respiratory secretions.
3. Antiallergic
Cetirizine hydrochloride can competitively inhibit the excitation of histamine H1 receptors on mast cell and eosinophil membranes by exogenous allergens, reduce their sensitization ability, and thus reduce allergic reactions.
4. Anti-inflammatory
Cetirizine hydrochloride can inhibit the release of inflammatory mediators such as histamine, thereby playing an anti-inflammatory role.
5. Immunomodulation
Cetirizine hydrochloride regulates the body's immune response by affecting the activity of immune cells to achieve the purpose of treatment.
Test | Specifications | Result |
---|---|---|
Appearance | A white or almost white crystalline | A white powder |
USP Standard comparision | USP Cetirizine Hydrochloride RS USP Cetirizine Related Compound A RS | Comforming |
Losson dry | ≤0.2% | 0.028% |
Heavy metal | ≤10ppm | 6ppm |
Total impurity | ≤0.3% | 0.12% |
acid | 1.2-1.8 | 1.5 |
Assay | 98.0-102.0% | 99.45% |
Salmonella | Negative | Negative |
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