What is Serrapeptase Powder
Serrapeptase powder, also known as Seradase powder is a proteolytic enzyme produced by bacteria of the genus Serratia. Serrapeptase can reduce inflammation and swelling, and can also reduce the viscosity of sputum and pus, making them thinner and easier to discharge. Serrapeptase is mainly used clinically to reduce swelling caused by surgery, trauma, chronic sinusitis patients and milk stasis in women; patients with respiratory diseases such as acute and chronic bronchitis, pneumonia, bronchiectasis, bronchial asthma, etc., can also take serrapeptase orally when the sputum is sticky and difficult to cough up; some patients after anesthesia also have sticky sputum and difficulty in coughing up sputum, and oral serrapeptase is also effective.
Pharmacological effects of serratiopeptidase powder
(1) Anti-inflammatory and swelling effects:
① Thermal burn rats were used as an inflammation model. After oral administration, the hyperpermeability of blood vessels was inhibited;
② Oral administration can inhibit the inflammatory edema of rat skin caused by anti-rat serum. It can also inhibit inflammatory edema in rats caused by various inflammatory substances such as carrageenan, dextran, 5-hydroxytryptamine, and bradykinin;
③ It has a strong ability to decompose the inflammatory polypeptide bradykinin in vitro;
④ It has a strong ability to dissolve fibrin and fibrinogen, but has almost no effect on body proteins such as albumin, α- and β-globulin.
(2) Promote the dissolution and excretion of sputum and thick liquid:
① For patients with chronic paranasal sinusitis, it can reduce the weight and viscosity of dry matter in nasal mucus;
② For rabbits suffering from subacute bronchitis due to exposure to sulfur dioxide gas, it can Significantly reduces sputum viscosity.
(3) The role of promoting the migration of antibiotics to the lesion:
① For patients with chronic paranasal sinusitis, it can promote the migration of ampicillin to the maxillary sinus;
② For rabbits with experimental cystitis, it can promote the migration of mecillin (azazamidine penicillin) to the bladder wall.
Metabokinetics of Serrapeptase Powder
Serratiopeptidase powder can be absorbed from the intestines after oral administration, but the amount is small. After oral administration, it can be widely distributed in tissues and body fluids such as lymph, bronchus, lung, bladder, blood, etc. The concentration in lymphoid tissue is the highest, and the concentration in tissues and blood is generally positively correlated with flow. When adults take 5 mg of serrapeptase, the peak time in blood and lymphoid tissue is about 1 hour, and the maintenance time is about 4 to 5 hours. The drug concentration in lymphoid tissue is longer than the blood concentration. Serrapeptase is metabolized in the body, and the main metabolites and some prototypes are The drug is excreted in feces and urine.
COA of Serrapeptase Powder
The efficacy of Serrapeptase Powder
1. Platelet aggregation inhibition
Serratia peptidase reduces platelet adhesion and aggregation by interfering with the signaling pathway of platelet activation factor, thereby reducing blood coagulation.
2. Fibrinolysis
Serratia peptidase powder can decompose fibrinogen into fibrin degradation products, dissolve the formed thrombus, and inhibit the activation of fibrinogen by thrombin, further blocking the process of fibrin monomer polymerization into fibrin polymer, so it has an anti-thrombotic effect.
3. Anti-inflammatory
Serratia peptidase can inhibit the production and release of inflammatory mediators such as interleukin-8, thereby playing an anti-inflammatory effect.
4. Hemostasis
Serratia peptidase can cleave fibrin in fibrin clots, dissolve it and achieve the purpose of hemostasis.
5. Promote wound healing
Because it has a certain anti-inflammatory effect, it is beneficial to reduce the inflammatory response after tissue damage, thereby promoting wound healing.
Quality Standards and Certifications
Our product adheres to the highest quality standards and holds numerous certifications, ensuring global recognition and trust:
FDA-Salis HALAL ISO CCRE5 USDA Organic EU Organic
Contact US
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